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Peptide design, synthesis, detection, purification, modification and coupling

Time:2019-11-26 11:09:24 Click:

Peptide synthesis is a process of repeated addition of amino acids ,The solid phase synthesis sequence is generally synthesized from C-terminal (carboxyl) to N-terminal (amino) In the past, polypeptide synthesis was carried out in a solution called liquid-phase synthesis.Since Merrifield successfully invented the solid-phase polypeptide synthesis method in 1963,After continuous improvement, the solid phase method has become a common technique in the synthesis of peptides and proteins,The advantages of the classical liquid synthesis method are unmatched,reducing the difficulty of product purification per step. polypeptide synthesis is generally divided into two types: solid-phase synthesis and liquid-phase polypeptide synthesis.

II. Technological process

Making amino acids in known order in a closed explosion-proof glass reactor .(sequence, usually from C-terminal-carboxyl-terminal Add, react, synthesize to N-terminal amino-terminal) and finally get the polypeptide carrier.To prevent side effects, The side chains of the amino acids involved in the reaction are protected.

III. Contents and criteria for reporting

Polypeptide products contain true and effective UPLC, mass spectrometry detection report.

The quality of the polypeptide.

IV. Fees and Service Cycles

Rates and service cycles vary depending on the sample provided by the customer ,Please contact Customer Service Officer for details or refer to the signed cooperation contract

V. Quality assurance

All the peptides in Bio-High were freeze-dried powder state and packaged with a special polypeptide tube. 

Enter into a polypeptide synthesis contract and confidentiality agreement (if necessary).

The polypeptide production cycle is 2-3 weeks, and the shortest time of short peptide (<15 peptides) is 1 week. The specific polypeptide production time is based on the specific sequence.

VI. After-sales service

The company will conduct customer visits on a regular basis to improve our service quality. The terms and conditions are governed by the contract of cooperation concluded and the details will vary according to the content of the contract. 


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